Deion Sanders and the Colorado Buffaloes (2-1) return home to Folsom Field to take on the Baylor Bears (2-1) on Saturday in the Big 12 opener for both teams. The Buffs are coming off a rivalry win over Colorado State last week, beating the Rams 28-9 in Fort Collins. Travis Hunter and Shedeur Sanders were outstanding for Colorado in the victory. Baylor is looking to build off a dominant 31-3 win over Air Force in Week 3. Safety Shilo Sanders (forearm) remains out for CU.

The Buffs are 1-point favorites in the latest Baylor vs. Colorado odds via SportsLine consensus, while the over/under for total points scored is 54. Colorado is a -125 (risk $125 to win $100) favorite on the money line, with Baylor listed as a +105 underdog (see up-to-date odds for every game this week on our college football odds page). 

Before you make any Colorado vs. Baylor picks or any other college football predictions, you NEED to see which side proven SportsLine expert Jimmie Kaylor is on. 

Kaylor is a NFL, college football and DFS expert for SportsLine, who has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America. His background as a former college football All-American and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks. He has his finger on the pulse of the college football landscape and has been cashing in big for the last two years. 

Kaylor destroyed the books in college football in 2023, netting a whopping 57.9 units while posting a 107-45-2 record. Anyone who followed his picks finished the season WAY UP!

Now, Kaylor has locked in a confident against-the-spread pick for Colorado vs. Baylor in their Week 4 matchup. We can tell you he's leaning Under on the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

Who wins Colorado vs. Baylor in their Week 4 matchup in Boulder and what critical X-factor makes one side of the spread a must-back? ... Join SportsLine right now to see which side of the spread to jump on, all from the expert who went 107-45-2, returning $5,790 for $100 bettors, betting on college football in 2023, and find out!